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- Bae3cad3b43e7c0c307e2d29c3b2adfd8 NCIT_P378 "NCI" @default.
- Bae3cad3b43e7c0c307e2d29c3b2adfd8 type Axiom @default.
- Bae3cad3b43e7c0c307e2d29c3b2adfd8 annotatedProperty IAO_0000115 @default.
- Bae3cad3b43e7c0c307e2d29c3b2adfd8 annotatedSource NCIT_C70675 @default.
- Bae3cad3b43e7c0c307e2d29c3b2adfd8 annotatedTarget "A gadolinium-based, hydrophilic, macrocyclic, electrically neutral contrast agent used in contrast-enhanced MRI (CE-MRI). Gadobutrol is a non-ionic, paramagnetic complex consisting of gadolinium (Gd3+) chelated with the macrocyclic compound dihydroxy-hydroxymethylpropyl-tetraazacyclododecane-triacetic acid (butrol). Following intravenous administration, gadobutrol may increase MRI sensitivity for the detection of tumors and inflammatory and demyelinating diseases of the central nervous system (CNS) that are associated with areas with blood-brain barrier defects due to altered perfusion or an enlarged extracellular space. This agent is eliminated in an unchanged form via the kidneys; extra-renal elimination is negligible." @default.