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- Bae7a2882a66608646cac9cf6ccfbcdc3 NCIT_P378 "NCI" @default.
- Bae7a2882a66608646cac9cf6ccfbcdc3 type Axiom @default.
- Bae7a2882a66608646cac9cf6ccfbcdc3 annotatedProperty IAO_0000115 @default.
- Bae7a2882a66608646cac9cf6ccfbcdc3 annotatedSource NCIT_C179630 @default.
- Bae7a2882a66608646cac9cf6ccfbcdc3 annotatedTarget "A preparation of donor-derived T-lymphocytes that have been genetically engineered to express a chimeric antigen receptor (CAR) directed against the tumor-associated antigen (TAA) CD7, with potential immunostimulating and antineoplastic activities. Upon intravenous administration, the allogeneic anti-CD7 CAR T cells specifically recognize and bind to CD7-expressing tumor cells, resulting in specific T-cell-mediated tumor cell lysis. CD7 is a transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. It is expressed in the majority of lymphoblastic T-cell leukemias and lymphomas and in a subset of peripheral T-cell lymphomas." @default.