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- Bae7b9b179a08dc182a73e08c0e912807 NCIT_P378 "NCI" @default.
- Bae7b9b179a08dc182a73e08c0e912807 type Axiom @default.
- Bae7b9b179a08dc182a73e08c0e912807 annotatedProperty IAO_0000115 @default.
- Bae7b9b179a08dc182a73e08c0e912807 annotatedSource NCIT_C29346 @default.
- Bae7b9b179a08dc182a73e08c0e912807 annotatedTarget "A substituted benzimidazole and proton pump inhibitor with antacid activity. Pantoprazole is a lipophilic weak base that crosses the parietal cell membrane and enters the acidic parietal cell canaliculus where it becomes protonated, producing the active metabolite sulphenamide, which forms an irreversible covalent bond with two sites of the H+/K+-ATPase enzyme located on the gastric parietal cell, thereby inhibiting both basal and stimulated gastric acid production." @default.