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- Baecb28e1c960f4ab1d817cedf241d8cb NCIT_P378 "NCI" @default.
- Baecb28e1c960f4ab1d817cedf241d8cb type Axiom @default.
- Baecb28e1c960f4ab1d817cedf241d8cb annotatedProperty IAO_0000115 @default.
- Baecb28e1c960f4ab1d817cedf241d8cb annotatedSource NCIT_C2235 @default.
- Baecb28e1c960f4ab1d817cedf241d8cb annotatedTarget "A cancer vaccine containing PR1, a 9 amino-acid human leukocyte antigen (HLA)-A2 restricted peptide derived from proteinase 3, with potential immunotherapeutic activity. Vaccination with PR1 leukemia peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing proteinase 3, resulting in tumor cell lysis. Often overexpressed in leukemic cells, proteinase 3 is a serine proteinase that activates progelatinase A and is involved in angiogenesis and metastasis." @default.