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- Bafeff7abdcf279d371fa833d7fc29ac0 NCIT_P378 "NCI" @default.
- Bafeff7abdcf279d371fa833d7fc29ac0 type Axiom @default.
- Bafeff7abdcf279d371fa833d7fc29ac0 annotatedProperty IAO_0000115 @default.
- Bafeff7abdcf279d371fa833d7fc29ac0 annotatedSource NCIT_C801 @default.
- Bafeff7abdcf279d371fa833d7fc29ac0 annotatedTarget "An orally bioavailable bis-dioxopiperazine and a derivative of the chelating agent ethylenediaminetetraacetic acid (EDTA) with antineoplastic, antiangiogenic, and antimetastatic activities. Razoxane specifically inhibits the enzyme topoisomerase II without inducing DNA strand breaks, which may result in the inhibition of DNA synthesis and cell division in the premitotic and early mitotic phases of the cell cycle. This agent may also exhibit antiangiogenic and antimetastatic activities although the precise molecular mechanisms of these actions are unknown." @default.