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- Bb1047bc63ce8918ea55d8da5285d23f8 NCIT_P378 "NCI" @default.
- Bb1047bc63ce8918ea55d8da5285d23f8 type Axiom @default.
- Bb1047bc63ce8918ea55d8da5285d23f8 annotatedProperty IAO_0000115 @default.
- Bb1047bc63ce8918ea55d8da5285d23f8 annotatedSource NCIT_C47650 @default.
- Bb1047bc63ce8918ea55d8da5285d23f8 annotatedTarget "The hydrochloride salt of palonosetron, a carbazole derivative and a selective serotonin receptor antagonist with antiemetic activity. Palonosetron competitively blocks the action of serotonin at 5-hydroxytryptamine type 3 (5-HT3) receptors located on vagal afferents in the chemoreceptor trigger zone (CTZ), resulting in suppression of chemotherapy-induced nausea and vomiting. The CTZ is located in the area postrema on the dorsal surface of the medulla oblongata at the caudal end of the fourth ventricle and outside the blood-brain barrier (BBB)." @default.