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- Bb22b3cb1dcad776ee406d82c70eaa668 NCIT_P378 "NCI" @default.
- Bb22b3cb1dcad776ee406d82c70eaa668 type Axiom @default.
- Bb22b3cb1dcad776ee406d82c70eaa668 annotatedProperty IAO_0000115 @default.
- Bb22b3cb1dcad776ee406d82c70eaa668 annotatedSource NCIT_C193463 @default.
- Bb22b3cb1dcad776ee406d82c70eaa668 annotatedTarget "A recombinant bispecific antibody targeting both the tumor-associated antigen (TAA) CD20 and the T-cell surface antigen CD3, with potential immunomodulating and antineoplastic activities. Upon administration, anti-CD20/CD3 bispecific antibody JS203 binds to both T-cells and CD20-expressing B-lineage tumor cells. The resulting cross-linkage may trigger a potent cytotoxic T-lymphocyte (CTL) response against CD20-expressing tumor B-cells. CD20 is exclusively expressed on B-cells during most stages of B-cell development and is often overexpressed in B-cell malignancies." @default.