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- Bb2ba8f7da65f85ae99beeeffbd0a00eb NCIT_P378 "NCI" @default.
- Bb2ba8f7da65f85ae99beeeffbd0a00eb type Axiom @default.
- Bb2ba8f7da65f85ae99beeeffbd0a00eb annotatedProperty IAO_0000115 @default.
- Bb2ba8f7da65f85ae99beeeffbd0a00eb annotatedSource NCIT_C98233 @default.
- Bb2ba8f7da65f85ae99beeeffbd0a00eb annotatedTarget "Any agent within the glitazar class that are dual or pan-acting peroxisome proliferator-activated receptor (PPAR) agonists with insulin sensitizing and lipid lowering activity. Glitarzars bind to two or more subtypes of PPAR isoforms, and result in improving hyperglycemia and lipid abnormalities as seen by decreasing levels of glucose, triglycerides and increasing levels of HDL cholesterol. These agents may be used to improve glucose tolerance without inducing adiposity and body weight gain. PPARs function as transcription factors that regulate expressions of genes involved in cellular differentiation, development, and metabolism (carbohydrate, lipid, protein), and tumorigenesis." @default.