Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Bb370d8c23e36cdfdcd438993a7dc6a0d> ?p ?o ?g. }
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- Bb370d8c23e36cdfdcd438993a7dc6a0d NCIT_P378 "NCI" @default.
- Bb370d8c23e36cdfdcd438993a7dc6a0d type Axiom @default.
- Bb370d8c23e36cdfdcd438993a7dc6a0d annotatedProperty IAO_0000115 @default.
- Bb370d8c23e36cdfdcd438993a7dc6a0d annotatedSource NCIT_C1839 @default.
- Bb370d8c23e36cdfdcd438993a7dc6a0d annotatedTarget "A yeast cell-derived recombinant polypeptide related to the naturally occurring, leech-derived anticoagulant hirudin. Lepirudin directly binds to and inactivates thrombin, producing dose-dependent increases in the activated partial thromboplastin time (aPTT) and prothrombin time (PT). The mechanism of action of this agent is independent of antithrombin III and is not inhibited by platelet factor 4. Natural hirudin, a family of highly homologous isopolypeptides, is produced in trace amounts by the leech Hirudo medicinalis." @default.