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- Bb3c121e673f7df1a60694cc58a8460f5 NCIT_P378 "NCI" @default.
- Bb3c121e673f7df1a60694cc58a8460f5 type Axiom @default.
- Bb3c121e673f7df1a60694cc58a8460f5 annotatedProperty IAO_0000115 @default.
- Bb3c121e673f7df1a60694cc58a8460f5 annotatedSource NCIT_C37899 @default.
- Bb3c121e673f7df1a60694cc58a8460f5 annotatedTarget "A benzoquinone antineoplastic antibiotic derived from the antineoplastic antibiotic geldanamycin. Tanespimycin binds to and inhibits the cytosolic chaperone functions of heat shock protein 90 (HSP90). HSP90 maintains the stability and functional shape of many oncogenic signaling proteins; the inhibition of HSP90 promotes the proteasomal degradation of oncogenic signaling proteins that may be overexpressed by tumor cells." @default.