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- Bb44e2e72a890c77cecc640931869ea3b NCIT_P378 "NCI" @default.
- Bb44e2e72a890c77cecc640931869ea3b type Axiom @default.
- Bb44e2e72a890c77cecc640931869ea3b annotatedProperty IAO_0000115 @default.
- Bb44e2e72a890c77cecc640931869ea3b annotatedSource NCIT_C2686 @default.
- Bb44e2e72a890c77cecc640931869ea3b annotatedTarget "A cancer vaccine adjuvant consisting of a recombinant fowlpox virus encoding human granulocyte-macrophage colony-stimulating factor (GM-CSF). GM-CSF binds to specific cell surface receptors on various immuno-hematopoietic cell types, enhancing their proliferation and differentiation and stimulating macrophage and dendritic cell functions in antigen presentation and antitumor cell-mediated immunity. Administration of recombinant fowlpox GM-CSF vaccine adjuvant may induce an immune response against tumor cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells." @default.