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- Bb46b22e7bf532cc8e25a94534d489aaa NCIT_P378 "NCI" @default.
- Bb46b22e7bf532cc8e25a94534d489aaa type Axiom @default.
- Bb46b22e7bf532cc8e25a94534d489aaa annotatedProperty IAO_0000115 @default.
- Bb46b22e7bf532cc8e25a94534d489aaa annotatedSource NCIT_C172614 @default.
- Bb46b22e7bf532cc8e25a94534d489aaa annotatedTarget "The hydrochloride salt form of galidesivir, an adenosine analog and RNA polymerase inhibitor, with potential broad-spectrum antiviral activity. Upon administration, galidesivir is metabolized to its monophosphate form, which is then converted into the active triphosphate nucleotide. Galidesivir triphosphate binds to viral RNA-dependent RNA polymerase (RdRp) and gets incorporated into the growing viral RNA strand, which leads to premature chain termination. This prevents viral transcription and replication." @default.