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- Bb4b6edc80be2513372e87f901504fbd4 NCIT_P378 "NCI" @default.
- Bb4b6edc80be2513372e87f901504fbd4 type Axiom @default.
- Bb4b6edc80be2513372e87f901504fbd4 annotatedProperty IAO_0000115 @default.
- Bb4b6edc80be2513372e87f901504fbd4 annotatedSource NCIT_C62076 @default.
- Bb4b6edc80be2513372e87f901504fbd4 annotatedTarget "An agent belonging to the glitazone class of antidiabetic agents with antihyperglycemic and anti-inflammatory activities. In addition to its selective affinity for peroxisome proliferator-activated receptor (PPAR) gamma and its ability to lower blood glucose levels, rosiglitazone also exerts anti-inflammatory activity through its ability to inhibit nuclear factor-kappaB (NF-KB) activity and increase I-kappaB levels. In addition, rosiglitazone may cause fluid retention and may worsen congestive heart failure. This agent is also associated with an increased risk of heart attacks." @default.