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- Bb55c9887243c89ca3756fa8e80d985a0 NCIT_P378 "NCI" @default.
- Bb55c9887243c89ca3756fa8e80d985a0 type Axiom @default.
- Bb55c9887243c89ca3756fa8e80d985a0 annotatedProperty IAO_0000115 @default.
- Bb55c9887243c89ca3756fa8e80d985a0 annotatedSource NCIT_C585 @default.
- Bb55c9887243c89ca3756fa8e80d985a0 annotatedTarget "A recombinant therapeutic agent which is chemically identical to or similar to the endogenous protein cytokine interleukin 1 (IL-1)-beta. Produced by monocytes and activated macrophages, endogenous mature IL-1 is generated through proteolytic cleavage by proteases such as IL-1-beta converting enzyme (ICE). This agent promotes angiogenesis, fibroblast proliferation, and neutrophil chemotaxis; it also regulates the functions of lymphocytes and epithelial cells and is involved in the 'acute phase response' to infection. (NCI04)" @default.