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- Bb6a3fa0de5ef0533d2bf6c7b0a55cbbb NCIT_P378 "NCI" @default.
- Bb6a3fa0de5ef0533d2bf6c7b0a55cbbb type Axiom @default.
- Bb6a3fa0de5ef0533d2bf6c7b0a55cbbb annotatedProperty IAO_0000115 @default.
- Bb6a3fa0de5ef0533d2bf6c7b0a55cbbb annotatedSource NCIT_C93170 @default.
- Bb6a3fa0de5ef0533d2bf6c7b0a55cbbb annotatedTarget "Any monoclonal antibody directed against the human tyrosine kinase vascular endothelial growth factor receptor (VEGFR), with potential anti-angiogenic and antineoplastic activities. An anti-VEGFR monoclonal antibody binds to and inhibits the activity of VEGFR, which may prevent the activation of downstream signaling pathways and tumor angiogenesis; the subsequent reduction in tumor nutrient supply may inhibit tumor cell proliferation. The expression of the pro-angiogenic growth factor VEGF is associated with tumor angiogenesis and tumor cell proliferation and invasion." @default.