Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Bb6ef2ccaa7bb03b44a1973ec16bc7341> ?p ?o ?g. }
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- Bb6ef2ccaa7bb03b44a1973ec16bc7341 NCIT_P378 "NCI" @default.
- Bb6ef2ccaa7bb03b44a1973ec16bc7341 type Axiom @default.
- Bb6ef2ccaa7bb03b44a1973ec16bc7341 annotatedProperty IAO_0000115 @default.
- Bb6ef2ccaa7bb03b44a1973ec16bc7341 annotatedSource NCIT_C26422 @default.
- Bb6ef2ccaa7bb03b44a1973ec16bc7341 annotatedTarget "This region represents the germline organization of the immunoglobulin heavy chain locus. The locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a D segment with a J segment; a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several D and J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. (from LocusLink)" @default.