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- Bb789ff79f89833eb24f3b7a4ce9e19b1 NCIT_P378 "NCI" @default.
- Bb789ff79f89833eb24f3b7a4ce9e19b1 type Axiom @default.
- Bb789ff79f89833eb24f3b7a4ce9e19b1 annotatedProperty IAO_0000115 @default.
- Bb789ff79f89833eb24f3b7a4ce9e19b1 annotatedSource NCIT_C182005 @default.
- Bb789ff79f89833eb24f3b7a4ce9e19b1 annotatedTarget "A human monoclonal antibody directed against human vascular endothelial growth factor receptor 2 (VEGFR-2; VEGFR2), with potential anti-angiogenesis and antineoplastic activities. Upon administration, pulocimab specifically binds to and inhibits VEGFR-2 on vascular endothelial cells, which may inhibit tumor angiogenesis and tumor cell proliferation. VEGFR-2, a tyrosine-protein kinase that plays an essential role in angiogenesis and the proliferation, survival, migration and differentiation of endothelial cells, is overexpressed in certain tumor types." @default.