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- Bb8e2cbd552cdc6a3c50ac55bf24b1f9c NCIT_P378 "NCI" @default.
- Bb8e2cbd552cdc6a3c50ac55bf24b1f9c type Axiom @default.
- Bb8e2cbd552cdc6a3c50ac55bf24b1f9c annotatedProperty IAO_0000115 @default.
- Bb8e2cbd552cdc6a3c50ac55bf24b1f9c annotatedSource NCIT_C1568 @default.
- Bb8e2cbd552cdc6a3c50ac55bf24b1f9c annotatedTarget "A saturated derivative of sphingosine. As an inhibitor of protein kinase C (PKC), safingol competitively binds to the regulatory phorbol-binding domain of PKC, a kinase involved in tumorigenesis. This agent has been shown to act synergistically with other chemotherapeutic agents and may potentiate chemotherapy drug-induced apoptosis in vitro and in vivo." @default.