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- Bb8f8420ac3f404430305b9d05cd22ee9 NCIT_P378 "NCI" @default.
- Bb8f8420ac3f404430305b9d05cd22ee9 type Axiom @default.
- Bb8f8420ac3f404430305b9d05cd22ee9 annotatedProperty IAO_0000115 @default.
- Bb8f8420ac3f404430305b9d05cd22ee9 annotatedSource NCIT_C47624 @default.
- Bb8f8420ac3f404430305b9d05cd22ee9 annotatedTarget "The hydrochloride salt form of molindone, a dihydroindolone compound with antipsychotic and anti-schizophrenic properties not structurally related to other major tranquilizers. Molindone hydrochloride exerts its effect by blocking dopamine receptors, probably D2 and D3, in the reticular activating and limbic systems, thereby decreasing dopamine excess in the brain. This leads to a reduction of spontaneous locomotion and aggressiveness, suppression of conditioned response, antagonism of stereotyped behaviour and hyperactivity induced by amphetamines." @default.