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- Bb9f9ed8a3358eceeba4c3a36d08628ac NCIT_P378 "NCI" @default.
- Bb9f9ed8a3358eceeba4c3a36d08628ac type Axiom @default.
- Bb9f9ed8a3358eceeba4c3a36d08628ac annotatedProperty IAO_0000115 @default.
- Bb9f9ed8a3358eceeba4c3a36d08628ac annotatedSource NCIT_C98233 @default.
- Bb9f9ed8a3358eceeba4c3a36d08628ac annotatedTarget "Any agent within the glitazar class that are dual or pan-acting peroxisome proliferator-activated receptor (PPAR) agonists with insulin sensitizing and lipid lowering activity. Glitarzars bind to two or more subtypes of PPAR isoforms, and result in improving hyperglycemia and lipid abnormalities as seen by decreasing levels of glucose, triglycerides and increasing levels of HDL cholesterol. These agents may be used to improve glucose tolerance without inducing adiposity and body weight gain. PPARs function as transcription factors that regulate expressions of genes involved in cellular differentiation, development, and metabolism (carbohydrate, lipid, protein), and tumorigenesis." @default.