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- Bba8cf2aa9a17e7693c7ffc3c4f9a4c35 NCIT_P378 "NCI" @default.
- Bba8cf2aa9a17e7693c7ffc3c4f9a4c35 type Axiom @default.
- Bba8cf2aa9a17e7693c7ffc3c4f9a4c35 annotatedProperty IAO_0000115 @default.
- Bba8cf2aa9a17e7693c7ffc3c4f9a4c35 annotatedSource NCIT_C82600 @default.
- Bba8cf2aa9a17e7693c7ffc3c4f9a4c35 annotatedTarget "A synthetic nonapeptide analogue of the natural gonadotrophin releasing hormone (GnRH) with potential antineoplastic activity. Deslorelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Continuous, prolonged administration of goserelin in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04)" @default.