Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Bbb27185e9193d8b7ba2772b6626f51c7> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- Bbb27185e9193d8b7ba2772b6626f51c7 NCIT_P378 "NCI" @default.
- Bbb27185e9193d8b7ba2772b6626f51c7 type Axiom @default.
- Bbb27185e9193d8b7ba2772b6626f51c7 annotatedProperty IAO_0000115 @default.
- Bbb27185e9193d8b7ba2772b6626f51c7 annotatedSource NCIT_C1679 @default.
- Bbb27185e9193d8b7ba2772b6626f51c7 annotatedTarget "A semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogues. (NCI04)" @default.