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- Bbbb3a8b2360f674e9657416f66956f3f NCIT_P378 "NCI" @default.
- Bbbb3a8b2360f674e9657416f66956f3f type Axiom @default.
- Bbbb3a8b2360f674e9657416f66956f3f annotatedProperty IAO_0000115 @default.
- Bbbb3a8b2360f674e9657416f66956f3f annotatedSource NCIT_C104748 @default.
- Bbbb3a8b2360f674e9657416f66956f3f annotatedTarget "A formulation containing an androgen receptor (AR) antagonist with potential antineoplastic activity. Darolutamide binds to ARs in target tissues; subsequently, inhibiting androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot translocate to the nucleus. This prevents binding to and transcription of AR-responsive genes that regulate prostate cancer cell proliferation. This ultimately leads to an inhibition of growth in AR-expressing prostate cancer cells." @default.