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- Bbbdbeb4c266c634d54bfadb0c8ffa88c NCIT_P378 "NCI" @default.
- Bbbdbeb4c266c634d54bfadb0c8ffa88c type Axiom @default.
- Bbbdbeb4c266c634d54bfadb0c8ffa88c annotatedProperty IAO_0000115 @default.
- Bbbdbeb4c266c634d54bfadb0c8ffa88c annotatedSource NCIT_C35424 @default.
- Bbbdbeb4c266c634d54bfadb0c8ffa88c annotatedTarget "Transformation of chronic lymphocytic leukemia into aggressive non-Hodgkin lymphoma, usually diffuse large B-cell lymphoma (immunoblastic or centroblastic variant). Occasional cases of transformation to Hodgkin lymphoma have also been described, particularly in patients treated with purine nucleotide analogues. Molecular genetic studies suggest that in approximately half of the cases, the lymphoma is clonally related to the underlying chronic lymphocytic leukemia, whereas in the remaining cases the lymphoma probably represents a secondary, unrelated neoplasm." @default.