Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Bbce5e8f56a677730a0efccf018184fb0> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- Bbce5e8f56a677730a0efccf018184fb0 NCIT_P378 "NCI" @default.
- Bbce5e8f56a677730a0efccf018184fb0 type Axiom @default.
- Bbce5e8f56a677730a0efccf018184fb0 annotatedProperty IAO_0000115 @default.
- Bbce5e8f56a677730a0efccf018184fb0 annotatedSource NCIT_C1848 @default.
- Bbce5e8f56a677730a0efccf018184fb0 annotatedTarget "A sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth factor I (IGF-I), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and tumor growth factor-beta (TGF-beta), to their receptors, thereby inhibiting endothelial cell proliferation and migration. This agent also inhibits vascular endothelial growth factor (VEGF)- and basic fibroblast growth factor (bFGF)-induced angiogenesis; retroviral reverse transcriptase; uncoupling of G-proteins from receptors; topoisomerases; cellular folate transport; and steroidogenesis." @default.