Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Bbd50dc957e082387626f25536e2debdf> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- Bbd50dc957e082387626f25536e2debdf NCIT_P378 "NCI" @default.
- Bbd50dc957e082387626f25536e2debdf type Axiom @default.
- Bbd50dc957e082387626f25536e2debdf annotatedProperty IAO_0000115 @default.
- Bbd50dc957e082387626f25536e2debdf annotatedSource NCIT_C1316 @default.
- Bbd50dc957e082387626f25536e2debdf annotatedTarget "An antagonist of the neurotransmitter dopamine with potential antineoplastic activity. 6-Hydroxydopamine (6-HOD) can be taken up by selective adrenergic terminals, thereby causing acute degeneration of adrenergic terminals that leads to depletion of norepinephrine, and of dopamine in the dopamine-sensitive sites. This agent is auto-oxidated at physiological pH that leads to the formation of reactive free radicals, thereby leading to cytotoxicity in neural cells. 6-Hydroxydopamine is often used to induce CNS and sympathetic neural lesions that model aging and various nervous disorders in animal systems." @default.