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- Bbd6b5d7b474b17f943521a93d9c1a88b NCIT_P378 "NCI" @default.
- Bbd6b5d7b474b17f943521a93d9c1a88b type Axiom @default.
- Bbd6b5d7b474b17f943521a93d9c1a88b annotatedProperty IAO_0000115 @default.
- Bbd6b5d7b474b17f943521a93d9c1a88b annotatedSource NCIT_C73815 @default.
- Bbd6b5d7b474b17f943521a93d9c1a88b annotatedTarget "The fumarate salt of cevipabulin, a synthetic, water soluble tubulin-binding agent with potential antineoplastic activity. Cevipabulin appears to bind at the vinca-binding site on tubulin, but seems to act more similar to taxane-site binding agents in that it enhances tubulin polymerization and does not induce tubulin depolymerization. The disruption in microtubule dynamics may eventually inhibit cell division and reduce cellular growth., a small, water soluble, synthetic tubulin-binding agent with potential antineoplastic activity. Cevipabulin appears to bind at the vinca-binding site on tubulin, but seems to act more similar to taxane-site binding agents in that it enhances tubulin polymerization and does not induce tubulin depolymerization. The disruption in microtubule dynamics may eventually inhibit cell division and may reduce cellular growth." @default.