Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Bbe578dda045ce2cb591696a5bdf16223> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- Bbe578dda045ce2cb591696a5bdf16223 NCIT_P378 "NCI" @default.
- Bbe578dda045ce2cb591696a5bdf16223 type Axiom @default.
- Bbe578dda045ce2cb591696a5bdf16223 annotatedProperty IAO_0000115 @default.
- Bbe578dda045ce2cb591696a5bdf16223 annotatedSource NCIT_C156175 @default.
- Bbe578dda045ce2cb591696a5bdf16223 annotatedTarget "An orally available capsule containing alkylglycerols and Rosmarinus officinalis extracts standardized to diterpenes, including carnosic acid and carnosol, with potential antineoplastic and anti-inflammatory activities. Upon administration, carnosic acid and carnosol may induce apoptosis by decreasing apoptosis regulator B-cell lymphoma 2 (Bcl-2) expression, decrease tumor cell growth through inhibition of mammalian target of rapamycin (mTOR) phosphorylation, and inhibit metastatic activity by preventing the adhesion of tumor cells to type I collagen and fibronectin. Additionally, these diterpenes may decrease inflammation by downregulating cyclooxygenase (COX) type 2 (COX-2) protein synthesis. Alkylglycerols (alkyl-Gro) are bioactive ether lipids that may, through a not yet fully elucidated mechanism, inhibit tumor cell growth and metastases." @default.