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- Bbe9b39e9f24daa4ffceb03e307fa99ab NCIT_P378 "NCI" @default.
- Bbe9b39e9f24daa4ffceb03e307fa99ab type Axiom @default.
- Bbe9b39e9f24daa4ffceb03e307fa99ab annotatedProperty IAO_0000115 @default.
- Bbe9b39e9f24daa4ffceb03e307fa99ab annotatedSource NCIT_C47675 @default.
- Bbe9b39e9f24daa4ffceb03e307fa99ab annotatedTarget "The acetate salt form of pirbuterol, a synthetic catecholamine and a pyridine derivative with sympathomimetic and bronchodilatory effects. Pirbuterol acetate selectively stimulates beta-2 adrenergic receptors, resulting in initiation of intracellular adenylate cyclase activity leading to increased levels of cAMP. As a result muscle relaxation (broncho- and vasodilation) occurs via cAMP-dependent signal transduction. In addition, elevated levels of cAMP inhibit release of inflammatory mediators from mast cells." @default.