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- Bbf4f9f7beea06844f8ae1ae08b70ddc1 NCIT_P378 "NCI" @default.
- Bbf4f9f7beea06844f8ae1ae08b70ddc1 type Axiom @default.
- Bbf4f9f7beea06844f8ae1ae08b70ddc1 annotatedProperty IAO_0000115 @default.
- Bbf4f9f7beea06844f8ae1ae08b70ddc1 annotatedSource NCIT_C2076 @default.
- Bbf4f9f7beea06844f8ae1ae08b70ddc1 annotatedTarget "A compound that inhibits the synthesis of the naturally occurring polyamines, intracellular compounds that bind to DNA and play a critical role in cell division, differentiation and membrane function. These inhibitors affect the activity of enzymes like ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (SAMD) that are involved in the biosynthesis of polyamines. A reduction in intracellular polyamine concentration may lead to a decreased cell growth." @default.