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- Bbf5bccf2a816a84aae87f780cc31756e NCIT_P378 "NCI" @default.
- Bbf5bccf2a816a84aae87f780cc31756e type Axiom @default.
- Bbf5bccf2a816a84aae87f780cc31756e annotatedProperty IAO_0000115 @default.
- Bbf5bccf2a816a84aae87f780cc31756e annotatedSource NCIT_C29050 @default.
- Bbf5bccf2a816a84aae87f780cc31756e annotatedTarget "The hydrochloride salt form of fexofenadine, a carboxylated metabolic derivative of terfenadine and second generation, long-lasting selective histamine H1 receptor antagonist, with antihistaminic activity. Upon administration, fexofenadine competitively binds of peripheral H1-receptors in the gastrointestinal (GI) tract, blood vessels, and bronchial smooth muscle. This prevents binding of histamine to peripheral H1-receptors and prevents their activation. This prevents a histamine-mediated allergic reaction. Fexofenadine does not cross the blood-brain-barrier (BBB)." @default.