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- Bbf8d366829656cca07c7f22cd2f1acb2 NCIT_P378 "NCI" @default.
- Bbf8d366829656cca07c7f22cd2f1acb2 type Axiom @default.
- Bbf8d366829656cca07c7f22cd2f1acb2 annotatedProperty IAO_0000115 @default.
- Bbf8d366829656cca07c7f22cd2f1acb2 annotatedSource NCIT_C504 @default.
- Bbf8d366829656cca07c7f22cd2f1acb2 annotatedTarget "A fluorinated pyrimidine monophosphate analogue of 5-fluoro-2'-deoxyuridine-5'-phosphate (FUDR-MP) with antineoplastic activity. As an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity. This agent is also metabolized to fluorouracil and other metabolites that can be incorporated into RNA and inhibit the utilization of preformed uracil in RNA synthesis. (NCI04)" @default.