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- Bbfcf7943de5250e740f64644e65a4ae1 NCIT_P378 "NCI" @default.
- Bbfcf7943de5250e740f64644e65a4ae1 type Axiom @default.
- Bbfcf7943de5250e740f64644e65a4ae1 annotatedProperty IAO_0000115 @default.
- Bbfcf7943de5250e740f64644e65a4ae1 annotatedSource NCIT_C151935 @default.
- Bbfcf7943de5250e740f64644e65a4ae1 annotatedTarget "A preparation of human T-lymphocytes engineered to express a chimeric antigen receptor (CAR) specific for the tumor-associated antigens (TAAs) cluster of differentiation 19 (CD19), CD20, CD22 and CD30, with potential immunostimulating and antineoplastic activities. Upon administration, the anti-CD19/CD20/CD22/CD30 CAR-T cells target and bind to CD19, CD20, CD22 and CD30 expressed on the surface of certain tumor cells. This induces selective toxicity in tumor cells expressing these TAAs. The TAAs are overexpressed in certain hematologic malignancies." @default.