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- Bc2085c4205ce30b0aab552de610be207 NCIT_P378 "NCI" @default.
- Bc2085c4205ce30b0aab552de610be207 type Axiom @default.
- Bc2085c4205ce30b0aab552de610be207 annotatedProperty IAO_0000115 @default.
- Bc2085c4205ce30b0aab552de610be207 annotatedSource NCIT_C29346 @default.
- Bc2085c4205ce30b0aab552de610be207 annotatedTarget "A substituted benzimidazole and proton pump inhibitor with antacid activity. Pantoprazole is a lipophilic weak base that crosses the parietal cell membrane and enters the acidic parietal cell canaliculus where it becomes protonated, producing the active metabolite sulphenamide, which forms an irreversible covalent bond with two sites of the H+/K+-ATPase enzyme located on the gastric parietal cell, thereby inhibiting both basal and stimulated gastric acid production." @default.