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- Bc22c6dd63816f24d631c86a6406218d5 NCIT_P378 "NCI" @default.
- Bc22c6dd63816f24d631c86a6406218d5 type Axiom @default.
- Bc22c6dd63816f24d631c86a6406218d5 annotatedProperty IAO_0000115 @default.
- Bc22c6dd63816f24d631c86a6406218d5 annotatedSource NCIT_C913 @default.
- Bc22c6dd63816f24d631c86a6406218d5 annotatedTarget "A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine tumor necrosis factor-alpha with antineoplastic properties. Tumor necrosis factor-alpha binds to and activates "death receptors" on the cell surface, resulting in apoptosis and cell death by the p53-independent extrinsic pathway. This agent also disrupts tumor vascularization. (NCI04)" @default.