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- Bc3085d7972c354520dc1f2e058a886c1 NCIT_P378 "KEGG" @default.
- Bc3085d7972c354520dc1f2e058a886c1 type Axiom @default.
- Bc3085d7972c354520dc1f2e058a886c1 annotatedProperty NCIT_P325 @default.
- Bc3085d7972c354520dc1f2e058a886c1 annotatedSource NCIT_C91497 @default.
- Bc3085d7972c354520dc1f2e058a886c1 annotatedTarget "Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that are activated by fatty acids and their derivatives. PPAR has three subtypes (PPARalpha, beta/delta, and gamma) showing different expression patterns in vertebrates. Each of them is encoded in a separate gene and binds fatty acids and eicosanoids. PPARalpha plays a role in the clearance of circulating or cellular lipids via the regulation of gene expression involved in lipid metabolism in liver and skeletal muscle. PPARbeta/delta is involved in lipid oxidation and cell proliferation. PPARgamma promotes adipocyte differentiation to enhance blood glucose uptake." @default.