Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Bc3c3b45dd096ce044219441046e2a372> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- Bc3c3b45dd096ce044219441046e2a372 NCIT_P378 "NCI" @default.
- Bc3c3b45dd096ce044219441046e2a372 type Axiom @default.
- Bc3c3b45dd096ce044219441046e2a372 annotatedProperty IAO_0000115 @default.
- Bc3c3b45dd096ce044219441046e2a372 annotatedSource NCIT_C1318 @default.
- Bc3c3b45dd096ce044219441046e2a372 annotatedTarget "The carbonate salt of lithium, a soft alkali metal, with antimanic and hematopoietic activities. Lithium interferes with transmembrane sodium exchange in nerve cells by affecting sodium, potassium-stimulated adenosine triphosphatase (Na+, K+-ATPase); alters the release of neurotransmitters; affects cyclic adenosine monophosphate (cAMP) concentrations; and blocks inositol metabolism resulting in depletion of cellular inositol and inhibition of phospholipase C-mediated signal transduction. The exact mechanism through which lithium exerts its mood-stabilizing effect has not been established. In addition, lithium stimulates granulocytopoiesis and appears to increase the level of pluripotent hematopoietic stem cells by stimulating the release of hematopoietic cytokines and/or directly acting on hematopoietic stem cells." @default.