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- Bc414b7f2deffbf6cd6a72ac9c7e69373 NCIT_P378 "NCI" @default.
- Bc414b7f2deffbf6cd6a72ac9c7e69373 type Axiom @default.
- Bc414b7f2deffbf6cd6a72ac9c7e69373 annotatedProperty IAO_0000115 @default.
- Bc414b7f2deffbf6cd6a72ac9c7e69373 annotatedSource NCIT_C99160 @default.
- Bc414b7f2deffbf6cd6a72ac9c7e69373 annotatedTarget "The hydrochloride salt form of icotinib, an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Icotinib selectively inhibits the wild-type and several mutated forms of EGFR tyrosine kinase. This may lead to an inhibition of EGFR-mediated signal transduction and may inhibit cancer cell proliferation. EGFR, a receptor tyrosine kinase, has been upregulated in a variety of cancer cell types." @default.