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- Bc4a3e67e11c261805cd6d3db6331ff95 NCIT_P378 "NCI" @default.
- Bc4a3e67e11c261805cd6d3db6331ff95 type Axiom @default.
- Bc4a3e67e11c261805cd6d3db6331ff95 annotatedProperty IAO_0000115 @default.
- Bc4a3e67e11c261805cd6d3db6331ff95 annotatedSource NCIT_C364 @default.
- Bc4a3e67e11c261805cd6d3db6331ff95 annotatedTarget "A biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is positively charged and reacts with the negatively charged microbial cell surface, thereby destroying the integrity of the cell membrane. Subsequently, chlorhexidine penetrates into the cell and causes leakage of intracellular components leading to cell death. Since gram positive bacteria are more negatively charged, they are more sensitive to this agent." @default.