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- Bc4d97562a6563754ad27e6edebc69a0e NCIT_P378 "NCI" @default.
- Bc4d97562a6563754ad27e6edebc69a0e type Axiom @default.
- Bc4d97562a6563754ad27e6edebc69a0e annotatedProperty IAO_0000115 @default.
- Bc4d97562a6563754ad27e6edebc69a0e annotatedSource NCIT_C80824 @default.
- Bc4d97562a6563754ad27e6edebc69a0e annotatedTarget "A purified, concentrated and sterile solution of horse-derived gamma globulin obtained by the immunization of horses with human T-lymphocytes, with T-cell depleting and immunosuppressive activities. Upon administration, horse anti-thymocyte globulin (hATG) specifically recognizes, modulates and destroys T-lymphocytes. Although the exact mechanism of action by which hATG causes immunosuppression is not completely understood, it is likely caused by a combination of T-lymphocyte depletion, reduction in T-cell activation and modulation of their cytotoxic activities. Administering of hATG prior to transplantation may reduce the risk of graft-versus-host disease (GvHD)." @default.