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- Bc4e851609b4c4b1cb73fa8ec12a3c6bb NCIT_P378 "NCI" @default.
- Bc4e851609b4c4b1cb73fa8ec12a3c6bb type Axiom @default.
- Bc4e851609b4c4b1cb73fa8ec12a3c6bb annotatedProperty IAO_0000115 @default.
- Bc4e851609b4c4b1cb73fa8ec12a3c6bb annotatedSource NCIT_C1193 @default.
- Bc4e851609b4c4b1cb73fa8ec12a3c6bb annotatedTarget "The trisodium salt of a synthetic organic analogue of inorganic pyrophosphate with antiviral activity. Foscarnet selectively blocks the pyrophosphate binding site of herpesvirus-specific DNA polymerases at concentrations that do not affect cellular DNA polymerases. This agent does not require phosphorylation by thymidine kinase (TK) or other kinases and therefore is active in vitro against herpes simplex virus (HSV) TK deficient mutants and cytomegalovirus (CMV) UL97 mutants. Because foscarnet crosses the blood brain barrier, it may be used in the treatment of viral infections of the CNS." @default.