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- Bc5215abbc254bdb120cc3a97a75b92fd NCIT_P378 "NCI" @default.
- Bc5215abbc254bdb120cc3a97a75b92fd type Axiom @default.
- Bc5215abbc254bdb120cc3a97a75b92fd annotatedProperty IAO_0000115 @default.
- Bc5215abbc254bdb120cc3a97a75b92fd annotatedSource NCIT_C200551 @default.
- Bc5215abbc254bdb120cc3a97a75b92fd annotatedTarget "A preparation of autologous T-lymphocytes genetically modified to express a T-cell receptor (TCR) specific for an as of yet undisclosed tumor-associated antigen (TAA), with potential antineoplastic activity. Peripheral blood mononuclear cells (PBMCs) are isolated from a patient, transduced with a TCR specific for the TAA, and expanded ex-vivo. Upon reintroduction into the patient, the autologous engineered TCR-T cells KSX01 target and bind to tumor cells expressing the TAA, which may induce cell death in and halt the growth of cancer cells expressing the undisclosed TAA." @default.