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- Bc59a80b1ba785f1782afc84a8a87cce7 NCIT_P378 "NCI" @default.
- Bc59a80b1ba785f1782afc84a8a87cce7 type Axiom @default.
- Bc59a80b1ba785f1782afc84a8a87cce7 annotatedProperty IAO_0000115 @default.
- Bc59a80b1ba785f1782afc84a8a87cce7 annotatedSource NCIT_C1096 @default.
- Bc59a80b1ba785f1782afc84a8a87cce7 annotatedTarget "An orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is phosphorylated by deoxycytidine kinase to a triphosphate form which competes with thymidine for incorporation into DNA; its incorporation into DNA inhibits DNA synthesis, resulting in tumor cell death and tumor necrosis. The presence of deoxycytidine kinase in a tumor is a determinant of tumor sensitivity to this drug. (NCI04)" @default.