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- Bc697cb947afb1ff419ecd438cb7bb142 hasDbXref "NCIT:C26964" @default.
- Bc697cb947afb1ff419ecd438cb7bb142 type Axiom @default.
- Bc697cb947afb1ff419ecd438cb7bb142 annotatedProperty IAO_0000115 @default.
- Bc697cb947afb1ff419ecd438cb7bb142 annotatedSource MONDO_0001341 @default.
- Bc697cb947afb1ff419ecd438cb7bb142 annotatedTarget "A dysgammaglobulinemia characterized by low or undetectable serum levels of immunoglobulin class A (IgA). It is the most common primary antibody deficiency. It may be inherited or the reversible sequela of infection or certain drugs. It may be caused by decreased or inefficient class-switching from progenitor B cells without any corresponding decreases in the other isotypes. Though affected persons may be asymptomatic, low levels of IgA will reduce the immune system's ability to combat infection where IgA is normally secreted, at mucosal surfaces. Selective IgA deficiency is seen in greater proportion among patients with autoimmune disorders." @default.