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- Bc6c2af2e2ba98b2882c50f28dcea51db NCIT_P378 "NCI" @default.
- Bc6c2af2e2ba98b2882c50f28dcea51db type Axiom @default.
- Bc6c2af2e2ba98b2882c50f28dcea51db annotatedProperty IAO_0000115 @default.
- Bc6c2af2e2ba98b2882c50f28dcea51db annotatedSource NCIT_C1870 @default.
- Bc6c2af2e2ba98b2882c50f28dcea51db annotatedTarget "A phosphorothioate antisense oligonucleotide. Targeted to the initiation codon region of the bcl-2 mRNA, oblimersen inhibits bcl-2 mRNA translation, resulting in decreased expression of the bcl-2 protein, an apoptotic inhibitor expressed in some types of cancer and linked to tumor drug resistance. This agent may enhance the efficacy of standard cytotoxic chemotherapy. (NCI04)" @default.