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- Bc7694d4ab10c98b6ad956fd81eef0dd8 NCIT_P378 "NCI" @default.
- Bc7694d4ab10c98b6ad956fd81eef0dd8 type Axiom @default.
- Bc7694d4ab10c98b6ad956fd81eef0dd8 annotatedProperty IAO_0000115 @default.
- Bc7694d4ab10c98b6ad956fd81eef0dd8 annotatedSource NCIT_C66981 @default.
- Bc7694d4ab10c98b6ad956fd81eef0dd8 annotatedTarget "An inhibitor of cathepsin K with potential anti-osteoporotic activity. Odanacatib selectively binds to and inhibits the activity of cathepsin K, which may result in a reduction in bone resorption, improvement of bone mineral density, and a reversal in osteoporotic changes. Cathepsin K, a tissue-specific cysteine protease that catalyzes degradation of bone matrix proteins such as collagen I/II, elastin, and osteonectin plays an important role in osteoclast function and bone resorption." @default.