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- Bc78eed71bcb811ec35695756ab7bfbb6 NCIT_P378 "NCI" @default.
- Bc78eed71bcb811ec35695756ab7bfbb6 type Axiom @default.
- Bc78eed71bcb811ec35695756ab7bfbb6 annotatedProperty IAO_0000115 @default.
- Bc78eed71bcb811ec35695756ab7bfbb6 annotatedSource NCIT_C62050 @default.
- Bc78eed71bcb811ec35695756ab7bfbb6 annotatedTarget "An anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin." @default.