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- Bc7dd629d5a2fbb1e3e7d5edea2612798 NCIT_P378 "NCI" @default.
- Bc7dd629d5a2fbb1e3e7d5edea2612798 type Axiom @default.
- Bc7dd629d5a2fbb1e3e7d5edea2612798 annotatedProperty IAO_0000115 @default.
- Bc7dd629d5a2fbb1e3e7d5edea2612798 annotatedSource NCIT_C65294 @default.
- Bc7dd629d5a2fbb1e3e7d5edea2612798 annotatedTarget "A semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefepime binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis." @default.