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- Bc8049b6cdd1f407d14292b6237cf9fed NCIT_P378 "NCI" @default.
- Bc8049b6cdd1f407d14292b6237cf9fed type Axiom @default.
- Bc8049b6cdd1f407d14292b6237cf9fed annotatedProperty IAO_0000115 @default.
- Bc8049b6cdd1f407d14292b6237cf9fed annotatedSource NCIT_C102853 @default.
- Bc8049b6cdd1f407d14292b6237cf9fed annotatedTarget "A monoclonal antibody directed against transforming growth factor-beta receptor type II (TGF-beta RII) with potential antineoplastic activity. Anti-TGF-beta RII monoclonal antibody IMC-TR1 specifically targets and binds to TGF-beta R11, thereby preventing the activation of TGF-beta RII-mediated signaling pathways. TGF-beta RII is mutated in a number of cancer cell types and is involved in cancer cell proliferation and tumor progression." @default.