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- Bc827e8b009d17c9d3cfe41b0b14a875b NCIT_P378 "NCI" @default.
- Bc827e8b009d17c9d3cfe41b0b14a875b type Axiom @default.
- Bc827e8b009d17c9d3cfe41b0b14a875b annotatedProperty IAO_0000115 @default.
- Bc827e8b009d17c9d3cfe41b0b14a875b annotatedSource NCIT_C1872 @default.
- Bc827e8b009d17c9d3cfe41b0b14a875b annotatedTarget "A synthetic indolocarbazole multikinase inhibitor with potential antiangiogenic and antineoplastic activities. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platelet-derived growth factor receptor (PDGFR) and FMS-like tyrosine kinase 3 (FLT3) tyrosine kinases, which may result in disruption of the cell cycle, inhibition of proliferation, apoptosis, and inhibition of angiogenesis in susceptible tumors." @default.